VIDEO FEATURE: Dr. Justin A. Maykel Performs Single Incision Colectomy at UMass Memorial Medical Center

November - Applied Medical's GelPOINT System was highlighted in a UMass Memorial Hospital video about single incision colon removal. In the video, Justin Maykel, MD, Chief of Colon and Rectal Surgery at UMass, explained a few of the potential advantages of single site colectomy: "Our goal is to basically minimize length of the incision and the number of the incisions. In doing so we hope that this actually translates into less pain for the patient, a faster recovery, [and] less wound related complications.."

PRODUCT LAUNCH: GelPOINT Path Transanal Access Platform

Rancho Santa Margarita, CA - October 20, 2011 - Applied Medical announced today the full market release of GelPOINT path transanal access platform. The GelPOINT path enables insufflated access through the anus and into the rectum and lower sigmoid colon for surgical procedures, such as Transanal Minimally Invasive Surgery (TAMIS), flap revision and fistula repair.

PRODUCT LAUNCH: Epix InLine Laparoscopic Instruments

September - Applied Medical enables advanced techniques with the release of Epix inline laparoscopic instruments. Epix instruments integrate naturally with the surgeon's hand, offering unmatched comfort and tactile feel.

PRODUCT LAUNCH: Alexis Laparoscopic System with Kii Fios First Entry

September - Applied Medical introduces the Alexis laparoscopic system, which enables a laparoscopic approach before and after specimen retrieval. The Alexis laparoscopic system consists of the Alexis O wound protector/retractor, which provides 360° of circumferential protection and retraction, a laparoscopic cap which maintains pneumoperitoneum, and a 12x100mm Kii Fios first entry that can be used as the first stick to insufflate with only 3mm penetration into the peritoneum.

MEDIA FEATURE: Applied Medical Expands Team, Leads List of Device Makers

August- Applied Medical is featured as one of the largest medical device companies in Orange County, CA on the Orange County Business Journal's 2011 list of medical device makers. In the past year Applied increased its local team by 24% and added more than 350 team members worldwide. Applied continues to grow as it meets the healthcare community's increasing demand for innovation, value and choice in the marketplace.

CLINICAL STUDY HIGHLIGHT: Alexis Wound Protector/Retractor

August - Applied Medical's Alexis wound protector/retractor appears in a study in Liver Transplantation, which found that "[t]he use of a wound protector significantly reduced wound complications." In a multivariate analysis of potential risk factors for wound infections in living donor partial hepatectomy, "only the use of a wound protector was found to significantly reduce the risk of wound infections in an adjusted analysis." ^REF

AWARD RECOGNITION: Applied Medical Granted Premier Pinnacle Award

July - Applied Medical has been honored with a Supplier Pinnacle Award at Premier Inc.'s 2011 Breakthroughs Conference and Exhibition. The Pinnacle Award recognizes suppliers who have demonstrated operational and quality excellence, as well as a commitment to meeting the clinical and economic needs of Premier's members. Applied was chosen from a select group of 39 top performing organizations to receive the award, out of a pool of over 800 contracted suppliers.

FACILITY EXPANSION: Applied Medical Adds Technology And Development Facility

July - Applied Medical announces the opening of a 52,000 square foot manufacturing and research facility. When fully operational, the multi-functional space will fulfill Applied's rapidly expanding research and operational requirements. This building brings the total square footage of Applied's Southern California headquarters to over 686,000 SF.

Applied's latest facility addition reflects the company's sustained growth as it continues to satisfy its customers' need for breakthrough technologies at a superior economic value. Since establishing its headquarters in Rancho Santa Margarita, CA in 2000, Applied has expanded its manufacturing space more than six-fold as it develops the next generation of medical devices for minimally invasive surgery.

Applied's significant investment in R&D and commitment to vertical integration has propelled Applied into one of the fastest growing laparoscopy companies in the country. Applied is now the second largest provider of trocars in the US, and holds market leadership in hand access laparoscopic procedures with approximately 85% market share (units).

Applied's rising presence in the marketplace has also led to significant team expansion. In 2010 alone, the company underwent a 14% team member increase. Applied has more than 2100 team members worldwide and over 1600 team members in Orange County. Applied is proud to be the largest employer in Rancho Santa Margarita and looks forward to being part of the community for years to come, as the company expands both locally and abroad.